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1.
Adv Tech Stand Neurosurg ; 46: 65-94, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37318570

RESUMO

Cerebellar mutism syndrome (CMS) has received increasing attention over the last decades as a complication of posterior fossa tumour surgery in children. Risk factors, aetiological aspects, and treatment measures of the syndrome have been investigated, yet the incidence of CMS remains unchanged. Overall, we are currently able to identify patients at risk, but we are unable to prevent it from occurring.Once CMS sets in, several symptomatic pharmacological treatments have been suggested, but only in smaller case series and not in randomized controlled trials, and it is not clear whether the treatment or time itself had a helpful effect.Within weeks to months, most patients regain their ability to speak after a phase with mutism or severely reduced speech; however, many patients continue to have speech and language deficits. At this point, anti-cancer treatment with chemotherapy and radiotherapy may be of focus more than the prognosis of CMS; however, many patients continue to have speech and language problems for months and years to come, and they are at high risk of other neurocognitive sequelae as well.Without reliable measures to prevent or treat the syndrome, we may look towards improving the prognosis of speech and neurocognitive functioning in these patients. As speech and language impairment is the cardinal symptom and late effect of CMS, the effect of intense and early-onset speech and language therapy as a standard of care in these patients should be investigated in relation to its effect on regaining speech capacity.


Assuntos
Neoplasias Encefálicas , Doenças Cerebelares , Neoplasias Infratentoriais , Mutismo , Criança , Humanos , Mutismo/diagnóstico , Doenças Cerebelares/diagnóstico , Neoplasias Encefálicas/complicações , Neoplasias Infratentoriais/complicações , Medição de Risco , Síndrome , Progressão da Doença , Complicações Pós-Operatórias/diagnóstico
2.
Child Dev ; 94(4): 889-904, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36880255

RESUMO

This study investigates the impact of evidentiality on source monitoring and the impact of source monitoring on false belief understanding (FBU), while controlling for short-term memory, age, gender, and receptive vocabulary. One hundred (50 girls) monolingual 3- and 4-year-olds from Turkey and the UK participated in the study in 2019. In Turkish, children's use of direct evidentiality predicted their source monitoring skills, which, in turn, predicted their FBU. In English, FBU was not related to source monitoring. Combined results from both languages revealed that Turkish-speaking children had better FBU than English-speaking children, and only for Turkish-speaking children, better source monitoring skills predicted better FBU. This suggests an indirect impact of evidentiality on FBU by means of source monitoring in Turkish.


Assuntos
Idioma , Linguística , Feminino , Criança , Humanos , Pré-Escolar , Turquia , Vocabulário , Memória de Curto Prazo
3.
Dev Psychol ; 57(8): 1210-1227, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-34591566

RESUMO

To examine whether children's acquisition of perspective-marking language supports development in their ability to reason about mental states, we conducted a longitudinal study testing whether proficiency with complement clauses around age 3 explained variance in false-belief reasoning 6 months later. Forty-five English-speaking 2- and 3-year-olds (23 female, Time 1 age range = 33-41 months) from middle-class families in the North-West of England took part in the study, which addresses a series of uncertainties in previous studies. We avoided the confound of using complement clauses in the false-belief tests, assessed complement-clause proficiency with a new comprehensive test designed to capture gradual development, and controlled for individual differences in executive functioning that could affect both linguistic and sociocognitive performance. Further, we aimed to disentangle the influence of two aspects of complement-clause acquisition: proficiency with the perspective-marking syntactic structure itself and understanding of the specific mental verbs used in this syntactic structure. To investigate direction of causality, we also tested whether early false-belief reasoning predicted later complement-clause proficiency. The results provide strong support for the hypothesis that complement-clause acquisition promotes development in false-belief reasoning. Proficiency with the general structure of complement-clause constructions and understanding of the specific mental verbs "think" and "know" in third-person complements at Time 1 both contributed uniquely to predicting false-belief performance at Time 2. However, false-belief performance at Time 1 also contributed uniquely to predicting complement-clause proficiency at Time 2. Together, these results indicate a bidirectional relationship between linguistic and sociocognitive development. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Assuntos
Desenvolvimento da Linguagem , Idioma , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Testes de Linguagem , Linguística , Estudos Longitudinais
4.
J Child Lang ; 42(6): 1237-66, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26435080

RESUMO

When learning their first language, children develop strategies for assigning semantic roles to sentence structures, depending on morphosyntactic cues such as case and word order. Traditionally, comprehension experiments have presented transitive clauses in isolation, and cross-linguistically children have been found to misinterpret object-first constructions by following a word-order strategy (Chan, Lieven & Tomasello, 2009; Dittmar, Abbot-Smith, Lieven & Tomasello, 2008; Hakuta, 1982; McDonald, 1989; Slobin & Bever, 1982). In an act-out study, we replicated this finding with Danish preschoolers. However, object-first clauses may be context-sensitive structures, which are infelicitous in isolation. In a second act-out study we presented OVS clauses in supportive and unsupportive discourse contexts and in isolation and found that five- to six-year-olds' OVS comprehension was enhanced in discourse-pragmatically felicitous contexts. Our results extend previous findings of preschoolers' sensitivity to discourse-contextual cues in sentence comprehension (Hurewitz, 2001; Song & Fisher, 2005) to the basic task of assigning agent and patient roles.


Assuntos
Compreensão , Sinais (Psicologia) , Semântica , Criança , Pré-Escolar , Feminino , Humanos , Idioma , Linguística , Masculino
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